Juve's 2-0 win in Portugal three weeks earlier ensured they went into the second leg in a comfortable position.
In European competition, they are unbeaten in their last 20 home games since losing 0-2 to Bayern Munich in the Champions League quarter-finals in April 2013.
Serie A champions Juventus have issued a hands-off warning to Arsenal regarding their manager Massimiliano Allegri after the Turin giants sealed their place in the Champions League quarter-finals.
It would take a very rare circumstance for Juventus to fail to advance past Porto and into the quarterfinals of the UEFA Champions League on Tuesday.
This was its third straight win since last season's title-winning coach Claudio Ranieri was sacked, with the team fighting a relegation battle in its Premier League title defence.
Any hope of a comeback from the visitors ended just before half-time when Porto defender Maxi Pereira was sent off for handball on the line.
"The first leg was hard for us because we were reduced to 10 men, but that happens in football", he said. Given the age I am, and in my second year, winning the Champions League would definitely be insane.
Dybala scored his second penalty in the last two games after that he had also scored a later victor in the last controversial Serie A game won against AC Milan last week.
"I think Real Madrid are the favourites, as they are the trophy holders, then Atletico Madrid, who reached the Final last season". If we get through we'll also be on the same level now.
So, just who has been selected for the match, as Porto try to find a route past Juve into the next round of the Champions League? "We can have a good game on Tuesday and ensure our fans go home happy with what they've seen at the stadium".
"We'd have everything to lose against them".
Allegri is not interested in sending a message to Juve's rivals to win the competition and simply wants to get the job done.
Paulo Dybala stepped up and made no mistake from 12-yards out to hand Juventus the lead on the night and made it 3-0 on aggregate.