The Portuguese league leaders will have to claw their way back from a 2-0 home defeat in the first leg, something which has never been done in the knockout stage since Europe's top club competition was reformed in 1992. If we get through we'll also be on the same level now.
Nevertheless, Dani Alves - who defeated Juve in the 2014-15 Champions League final during his time at Barcelona - is confident the Bianconeri have what it takes to go one better this term.
"I expected it to be a strong Juve side when I arrived, because a team that wins five consecutive Scudetto titles and reaches the Champions League final has to be strong. But a lot of things happen in football - we've seen it all", said Spain goalkeeper Iker Casillas, who appeared to be referring to Barcelona's comeback against Paris St-Germain last week. "Now the most important part of the season is coming and the great players work all year to be ready for these moments, those in which you have to win competitions".
Against Porto, Juventus will be boosted by the return of Juan Cuadrado from suspension and Mario Mandzukic from illness.
However, Porto have only progressed past the round of 16 once in their last six Champions League attempts.
Paolo Dybala scored the only goal of an unspectacular victory late in the first half, dispatching a penalty that followed the sending off of Maxi Pereira.
"It would be insane to win the Champions League at my age because I only joined Juventus two years ago", Dybala said.
Porto striker Andre Silva has been directly involved in two thirds of Porto's goals in this season's Champions League, scoring four and assisting two.