Bayer Leverkusen have to believe they can succeed at Atletico - Tayfun Korkut

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"We will not be beaten in Madrid, we will go and fight in the tie until the end".

However the Colchoneros coach told his prematch news conference that whatever the situation, his side only knew one way of playing the game - to start with intensity and go out to win.

In fact, Bayer Leverkusen have lost nine of their last 10 Champions League knockout games (W1), their only win in that run coming against Atletico Madrid (1-0, February 2015). "We need to give our all again on Wednesday", said the Spanish global.

Los Rojiblancos are massive favorites against Leverkusen who are now 10th in the Bundesliga, with SportyBet offering Atletico odds of (1.64) for the win while Leverkusen can be backed at (5.25) and the draw is offered at (4.03).

Having replaced Roger Schmidt, sacked after the 6-2 Bundesliga defeat at Dortmund earlier this month, Korkut urged his players to approach the game in a positive way.

Frenchman Griezmann has six goals in his last seven games, with his 84th minute strike helping the Rojiblancos to a 1-0 win at Granada on Saturday.

Turkey worldwide defender Omer Toprak will also miss the game in the Spanish capital because of an ankle problem sustained in the weekend draw with Werder Bremen, with Jonathan Tah, Lars Bender and Stefan Kiessling already on the treatment table.

Atletico will be without defender Filipe Luis and captain Gabi due to suspension after they both received their third yellow cards of the tournament during the first leg at the BayArena.

Atletico Madrid manager Diego Simeone addresses the media the day before his team's match against Bayer Leverkusen.

What: Atletico Madrid hosts Bayer Leverkusen in the UEFA Champions League Round of 16 second leg.

However, that has not stopped the optimism of the German supporters, 1,200 of whom will follow their side to the Vicente Calderon. They're opponents who know how to suffer and get results.

Yannick Carrasco has had to step up and deliver more goals this season, with Kevin Gameiro not being quite as prolific as they'd hoped. They'll keep the ball, take the sting out of the game and wait for a chance to come to pick their visitors off.